Anti-VPS26B Antibody

Product Name

Anti-VPS26B Antibody

View all VP26B Antibodies

SKU/Catalog Number

A12325

Size

100μl

Form

Liquid

Description

Boster Bio Anti-VPS26B Antibody catalog # A12325. Tested in WB applications. This antibody reacts with Human, Mouse.

Storage & Handling

Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.

Cite This Product

Anti-VPS26B Antibody (Boster Biological Technology, Pleasanton CA, USA, Catalog # A12325)

Host

Rabbit

Contents

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Clone Number

F7E4

Isotype

IgG

Immunogen

Synthesized peptide derived from the Internal region of human VPS26B. at AA rangle: 200-280

*Blocking peptide can be purchased. Costs vary based on immunogen length. Contact us for pricing.

Reactive Species

A12325 is reactive to Vps26b in Human, Mouse

Applications

A12325 is guaranteed for WB Boster Guarantee

Observed Molecular Weight

Calculated molecular weight

39.125kDa

Background of VP26B

COBRA1 (cofactor of BRCA1) also known as NELF-B, is an essential component of the negative elongation factor (NELF) complex. COBRA1 has been shown to directly bind estrogen receptor alpha (ERα) and repress ERα-mediated transcription (Aiyar SE et al., 2004). COBRA1 has also been demonstrated to interact with c-Jun and c-Fos suggesting a role in modulation of the AP-1 pathway and therefore may be important in cell proliferation, differentiation, apoptosis and oncogenesis (Zhong H et al., 2004)

Antibody Validation

Boster validates all antibodies on WB, IHC, ICC, Immunofluorescence, and ELISA with known positive control and negative samples to ensure specificity and high affinity, including thorough antibody incubations.

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Assay Dilutions Recommendation

The recommendations below provide a starting point for assay optimization. The actual working concentration varies and should be decided by the user.

WB, 1:500-1:2000

Validation Images & Assay Conditions

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Western Blot (WB) analysis of LOVO cells using VPS26B Polyclonal antibody.

Gene/Protein Information For Vps26b (Source: Uniprot.org, NCBI)

Alternative Names

MGC10485; Pep8b; vacuolar protein sorting 26 homolog B (S. pombe); vacuolar protein sorting 26 homolog B (yeast); vacuolar protein sorting-associated protein 26B; Vesicle protein sorting 26B Vps26b|1810012I05Rik, 2310075A12Rik, AI848392|VPS26 retromer complex component B|vacuolar protein sorting-associated protein 26B|vacuolar protein sorting 26 homolog B|vesicle protein sorting 26B

For more info on Vps26b, check out the Vps26b Infographic

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In this infographic, you will see the following information for Vps26b: database IDs, superfamily, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post-translational modifications, and related diseases, research areas & pathways. If you want to see more information included, or would like to contribute to it and be acknowledged, please contact [email protected].

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